Publications - Xiaolei Xu, Ph.D.

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1. Zhang R, Yang J, Zhu J, Xu X. Depletion of zebrafish Tcap leads to muscular dystrophy via disrupting sarcomere-membrane interaction, not sarcomere assembly. Hum Mol Genet 2009 Nov 1; 18(21):4130-40. Epub 2009 Aug 12.
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2. Huang W, Zhang R, Xu X. Myofibrillogenesis in the developing zebrafish heart: A functional study of tnnt2. Dev Biol 2009 Jul 15; 331(2):237-49. Epub 2009 May 07.
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3. Huang W, Zhang RL, Xu XL. Myofibrillogenesis in the developing zebrafish heart: A functional study of tnnt2. Dev Biol 2009 Jul 15; 331(2):237-49.
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4. Zhang R, Xu X. Transient and transgenic analysis of the zebrafish ventricular myosin heavy chain (vmhc) promoter: an inhibitory mechanism of ventricle-specific gene expression. Dev Dyn 2009 Jun; 238(6):1564-73.
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5. Lin X, Xu X. Distinct functions of Wnt/beta-catenin signaling in KV development and cardiac asymmetry. Development 2009 Jan; 136(2):207-17.
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6. Sun X, Hoage T, Bai P, Ding Y, Chen Z, Zhang R, Huang W, Jahangir A, Paw B, Li YG, Xu X. Cardiac hypertrophy involves both myocyte hypertrophy and hyperplasia in anemic zebrafish. PLoS One 2009; 4(8):e6596. Epub 2009 Aug 12.
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7. Chen Z, Huang W, Dahme T, Rottbauer W, Ackerman MJ, Xu X. Depletion of zebrafish essential and regulatory myosin light chains reduces cardiac function through distinct mechanisms. Cardiovasc Res 2008 Jul 1; 79(1):97-108. Epub 2008 Mar 14.
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8. Sun X, Zhang R, Lin X, Xu X. Wnt3a regulates the development of cardiac neural crest cells by modulating expression of cysteine-rich intestinal protein 2 in rhombomere 6. Circ Res 2008 Apr 11; 102(7):831-9. Epub 2008 Feb 21.
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9. Lin X, Rinaldo L, Fazly AF, Xu X. Depletion of Med10 enhances Wnt and suppresses Nodal signaling during zebrafish embryogenesis. Dev Biol 2007 Mar 15; 303(2):536-48.
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10. Rich A, Leddon SA, Hess SL, Gibbons SJ, Miller S, Xu X, Farrugai G. Kit-like immunoreactivity in the zebrafish gastrointestinal tract reveals putative ICC. Dev Dyn 2007 Mar; 236(3):903-11.
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11. Seeley M, Huang W, Chen Z, Wolff WO, Lin X, Xu X. Depletion of zebrafish titin reduces cardiac contractility by disrupting the assembly of Z-discs and A-bands. Circ Res 2007 Feb 2; 100(2):238-45. Epub 2006 Dec 14.
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12. Wang L, Dutta SK, Kojima T, Xu X, Khosravi-Far R, Ekker SC, Mukhopadhyay D. Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival. PLoS One 2007; 2(11):e1161. Epub 2007 Nov 14.
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13. Wang L, Mukhopadhyay D, Xu X. C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis. FASEB J 2006 Jul; 20(9):1513-5. Epub 2006 Jun 05.
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14. Bos JM, Poley RN, Ny M, Tester DJ, Xu X, Vatta M, Towbin JA, Gersh BJ, Ommen SR, Ackerman MJ. Genotype-phenotype relationships involving hypertrophic cardiomyopathy-associated mutations in titin, muscle LIM protein, and telethonin. Mol Genet Metab 2006 May; 88(1):78-85. Epub 2005 Dec 13.
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15. J, Martijn Bos Rainer N, Poley Melissa Ny David J, Tester Xiaolei Xu Matteo Vatta Jeffrey A, Towbin Bernard J, Gersh Steve R, Ommen, Michael J, Ackerman. Genotype–phenotype relationships involving hypertrophic cardiomyopathy-associated mutations in titin, muscle LIM protein, and telethonin. Molecular Genetics and Metabolism 2006; 88(1):78-85.
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16. Xu X, Meiler SE, Zhong TP, Mohideen M, Crossley DA, Burggren WW, Fishman MC. Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin. Nat Genet 2002 Feb; 30(2):205-9.
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17. Zaffran S, Xu X, Lo PC, Lee HH, Frasch M. Cardiogenesis in the Drosophila model: control mechanisms during early induction and diversification of cardiac progenitors. Cold Spring Harb Symp Quant Biol 2002; 67:1-12.
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18. Nguyen HT, Xu X. Drosophila mef2 expression during mesoderm development is controlled by a complex array of cis-acting regulatory modules. Dev Biol 1998 Dec 15; 204(2):550-66.
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19. Xu X, Yin Z, Hudson JB, Ferguson EL, Frasch M. Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm. Genes Dev 1998 Aug 1; 12(15):2354-70.
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20. Yin Z, Xu X, Frasch M. Regulation of the twist target gene tinman by modular cis-regulatory elements during early mesoderm development. Development 1997 Dec; 124(24):4971-82.
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21. Zhou Y, Xu X, Liu Z, Zhao S. Analysis of the transcriptional regulation by the 5’-upstream sequences of Tumor Necrosis Factor. Chinese Science Bulletin 1992; 37(1):74-7.
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22. Rich A, Leddon SA, Hess SL, Gibbons SJ, Miller S, Xu X, Farrugai G. Kit-like immunoreactivity in the zebrafish gastrointestinal tract reveals putative ICC. Dev Dyn 2007 Mar; 236(3):903-11.
    View PubMed