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Mayo Clinic Protein Core

ABOUT US

The MPRC Peptide Synthesis Facility, formerly known as The Protein Core, was established as a shared research resource on the Mayo Rochester campus in 1984. Daniel McCormick, Ph.D. is the facility's founder and current director. The facility, along with the Mayo Clinic Cancer Center and the General Clinical Research Center are part of the Mayo genomic and proteomic effort. The facility is housed in Guggenheim 1633 and comprises part of the Mayo Proteomics Research Center (MPRC). The facility provides services in peptide synthesis to Mayo investigators and also conducts research and development of new methods in the field of solid phase peptide synthesis.

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ABOUT DR. McCORMICK

Dr. Daniel McCormick is the founder of the Mayo Peptide Synthesis Facility ( est. 1984) and Co-director of Mayo Proteomics Research Center. Doctor McCormick is a protein biochemist with special interest in the structural and immunological analysis of proteins. In addition, Doctor McCormick received his post-doctoral training (1981-1984) in the field of peptide synthesis by Merrifield solid phase methods, and currently uses this method to explore the antigenic structure of proteins ( i.e., T- and B-cell epitopes).

Dr. McCormick holds six U.S. patents and two international patents, with his latest patent describing the repression of gene expression by Peptide Nucleic Acid (PNA) oligomers (US Patent # 6, 743, 627). He has published over 110 peer-reviewed publications in the field of protein structure analysis, and in the application of peptide synthesis to examine the structural function of protein ligands, receptors, and T-cell epitopes.

Currently, Dr. McCormick is an active member of eight scientific societies including the American Chemical Society (ACS), the American Association of Immunologists (AAI), the American Society for Biochemistry and Molecular Biology (ASBMB), and the Protein Society. In addition, Dr. McCormick also serves as an ad hoc referee for several journals, which include The Journal of Peptide Research, Protein Science, and Analytical Biochemistry.

Photo of Daniel J         McCormick Ph.D.
"For the past two decades, synthetic peptides have been used as invaluable tools to examine the functional attributes of proteins in unambiguous detail."

Professor: Biochemistry and Molecular Biology,
Mayo Clinic College of Medicine

Co-Director: Mayo Proteomics Research Center

Director: Mayo Peptide Synthesis Facility



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