| Date | Speaker | Presentation |
| 1/13/2006 | Christopher G. Chute, M.D., DrPH Professor, Medical Informatics Chair, Division of Biomedical Informatics Mayo Clinic | "Research Roadmaps, IT Infrastructure, and Biomedical Informatics: NIH’s CTSA as a Unifying Paradigm" Presentation Slides |
| 2/10/2006 | John P. Pestian, Ph.D., MBA Director, Computational Medicine Center Cincinnati Children Hospital Medical Center | "Classifying Clinical Free Text - The Auto-ontologizer: A work in progress" |
| 3/10/2006 | Nathan Pankratz, PhD Postdoctoral Fellow Indiana University, School of Medicine | "Understanding the genetic contribution to Parkinson disease" |
| 4/7/2006 | Ping-I Lin, MD, PhD Research Associate Duke University Medical Center | "Interrogating Contradictory Flip-flop Allelic Associations with Disease Risk" |
| 5/5/2006 | Shaoqi Rao, PhD Assistant Professor Cleveland Clinic Foundation | "Unraveling the genetic mechanisms for complex human diseases" |
| 5/11/2006 | Joanna Biernacka, PhD Postdoctoral Research Associate Cambridge Institute for Medical Research University of Cambridge, United Kingdom | "Methods for identification of polymorphisms responsible for a linkage signal with application to type 1 diabetes" |
| 7/14/2006 | Nina Schwenk, MD Hugh Smith, MD David Mohr, MD Mayo Clinic College of Medicine | "Update on Mayo-IBM Collaboration and Developing Enterprise Data Trust (EDT) Activities" |
| 8/11/2006 | Sue Ellen Wright, PhD Professor, Institute for Applied Linguistics Kent State University | "Typologies for Knowledge Representation Resources" |
| 8/15/2006 | Douglas B. Fridsma, MD, PhD, FACP Assistant Professor, Center for Biomedical Informatics and Intelligent Systems University of Pittsburgh | "The BRIDG Project: A Model to Improve Clinical Trials Research" |
| 9/18/2006 | Diago Fraidenraich, PhD Senior Research Scientist Memorial Sloan-Kettering Cancer Center | "Defects in Mice by Early Injection of Embryonic Stem Cells" |
| 10/16/2006 | Jeffrey W. Walker, PhD Professor of Physiology Director of University of Wisconsin Human Proteomics Program | "Endothelin Signaling and Heart Failure" |